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doi:10.1016/s0092-8674(00)81271-4
A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation
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G6PD-deficient cells are unable to generate enough NADPH under the condition of severe thiol depletion and GSH biosynthesis and methionine cycle are upregulated at the expense of ATP but fail to compensate for GSH depletion (311)
For comparative analyzes, we focused on three key time points: Day 1 (fed), Day 2 (fasted), and Day 3 (refed)
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