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Multidisciplinary support is crucial and may include: Dietetic input to establish regular, balanced eating patterns without rigid restriction Specialist eating disorder services for complex presentations Support groups (such as Beat, the UK eating disorder charity) Treatment of co-occurring conditions such as depression, anxiety, or substance use disorders Patients should be encouraged to access NHS talking therapies through self-referral or GP referral
Some patients benefit most from a supervised combination based on their health profile
For the validation cohort (2021), a similar protocol than above was used in 96 well plates with the following modifications: Digestion was made with 0.25 g of trypsin only, acidification was performed with formic acid 1% (FA)
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Ahmed TJ, Montero-Melendez T, Perretti M, Pitzalis C
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