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Large studies in humans have not shown a clear link to increased thyroid cancer, but the medication remains restricted for those with a personal or family history of Medullary Thyroid Cancer or MEN 2 syndrome as a precaution

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Semaglutide-glycine blends and tirzepatide-glycine compounds are formulations that combine the GLP-1 medication with glycine, an amino acid that may enhance tolerability

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