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We evaluated the efficacy and safety of 24-week treatment of mazdutide up to 6 mg in Chinese overweight adults or adults with obesity, as an interim analysis of a randomised, two-part (low doses up to 6 mg and high dose of 9 mg), double-blind, placebo-controlled phase 2 trial (ClinicalTrials.gov, NCT04904913)

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Studies suggest both semaglutide and liraglutide may slightly increase the risk of thyroid tumors, including medullary thyroid carcinoma (MTC)