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Both monothiol roGFP2 variants were rapidly glutathionylated with residue C208 reacting about twice as fast as residue C151 regardless whether PfGrx C32S/C88S (SSG) or PfGrx C88S (SSG) was used as the oxidant
Weight, BMI, blood pressure, laboratory results, and current medications may also be assessed
It also describes their side effect profiles as broadly similar, with nausea and vomiting common early and typically subsiding during titration, though it flags tirzepatide's gastrointestinal effects as potentially more closely tied to the amount taken
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