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However, patients require closer monitoring of hydration status, blood pressure, and renal function, as the combination may increase dehydration risk, particularly during gastrointestinal side effects or dose escalation periods
Physicians frequently encounter incomplete or inadequate requests from dental practices, including missing clinical details, unclear surgical timelines, and in some cases, no formal clearance documentation at all
The medication's effect on bowel habits appears highly individualised, influenced by factors such as baseline gut function, dietary habits, hydration status, concurrent medications, and the specific dose being administered
