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Things like GHRP3 can potently increase growth hormone, but are known to also potently increase prolactin and cortisol, leading to more than a doubling of circulating cortisol, which depending on how well regulated it is across the time of day can be problematic
Long-term benefits, such as improved mood and cognitive function, may become more noticeable with regular treatments over time
Epitalon's effects come from short-term courses that reset cellular and circadian mechanisms rather than continuous exposure
They ended up being in the 300s
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