This article examines the theoretical application sites and best practices for GLP-1 patches, should such formulations become available, drawing on established principles for transdermal medication delivery systems used in UK clinical practice
Santhosh C
Using gene-edited mice with humanised GLP-1 receptors, the team found that oral small-molecule GLP-1 drugs activated the central amygdala, a region associated with desire and reward that sits deeper in the brain than the hypothalamic and hindbrain networks where injectable peptide GLP-1s have been shown to act
Polymorphisms of cystathionine beta-synthase gene are associated with susceptibility to sepsis
Lack of glutathione contributes to oxidative stress, which plays a key role in lung disease, osteoarthritis, cataracts, glaucoma, chemotherapy, and cancer, as well as Alzheimers disease and Parkinsons disease (Wu et al., 2004)