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By integrating these omes, we identified distinct AML subtypes, genotypephenotype associations, biomarkers and pathobiological mechanisms

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Engineering of gasdermin D-cleaving proteases Although the evolved X(GD_L) proteases displayed promising activity through profiling activity in the PACE architecture, they failed to yield measurable kinetic parameters or substrate cleavage in mammalian cells, likely due to insufficient catalytic activity (Fig

SELENOW contains a selenocysteine residue and a cysteine residue that binds to a glutathione molecule, suggesting a role in redox regulation (18)

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