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This requires a constant undisturbed flow of oxygen from the breathing air with sufficient oxygen partial pressure via the respiratory tract, the passage of oxygen through the pulmonary blood barrier of the pulmonary alveoli, the diffusion through the erythrocyte membrane, the formation of hemoglobin and detachment from the hemoglobin in the blood capillaries of the tissue Diffusion of oxygen through the interstitial space, the interstitial space, through the Cell membrane and the mitochondrial membrane up to the respiratory chain described above

Verdict: Limited evidence overall DSIP has some preliminary human sleep data, but most broader claims remain unproven, and safety uncertainty is substantial [24][14]

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