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The study concludes that DSIPs activating action on oxidative phosphorylation and its preventive effects under hypoxia provide a strong basis for understanding its previously reported stress-protective and antioxidant actions in vivo

Moreover, because non-cancerous cells, including immune cells, also have metabolic vulnerabilities, drugs targeting metabolism may affect tumor cell metabolism and other components within the TME, potentially leading to immunosuppression or severe adverse effects [319]

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