Major challenges in NDDS include biocompatibility, biodegradability, immune-evasion efficacy, solubility and stability in biological environments, and the potential for off-target effects
Cost and insurance coverage challenges Monthly costs range from $200 for compounded products to nearly $1,850 for brand-name versions without insurance
16,17 Under such adverse factors, drug repurposing, namely repositioning and reevaluating marketed or investigational drugs for identifying and confirming new indications, has become an important method for drug discovery
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Existing liver conditions and other factors can complicate the assessment of semaglutide's impact on the liver