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The relationship between weight loss and OSA improvement varies considerably between individuals, and some patients may continue to require PAP therapy despite significant weight reduction

Spread protein across several smaller feedings rather than one or two large meals your appetite cannot finish

Pediatr Res 14:11271131 Matsuishi T, Stumpf DA, Seliem M, Eguren LA, Chrislip K (1991) Propionate mitochondrial toxicity in liver and skeletal muscle: acyl CoA levels

Escalation: If tolerated, the dose is increased to the next level (e.g., 7 mg, then 14 mg) every 4 weeks

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