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A new covalent GPX4 inhibitor, C18, shown strong inhibitory efficacy against TNBC cells and substantial tumour growth suppression in a xenograft model, with no apparent toxicity [268]
Both T2DM and T1DM are associated with a significantly increased risk of bone abnormalities and fractures
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Ageing and inflammation - a central role for mitochondria in brain health and disease
Patients who dose-escalate slowly (starting at 0.25 mg weekly, increasing by 0.25 mg every 4 weeks) report fewer and less intense GI symptoms than those who jump directly to higher doses
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