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Since cardiovascular complications of diabetes (62, 63) as well as diabetic nephropathy (64) are associated with an imbalance in the activity of RAAS, the interaction with this system could explain some of the beneficial effects of GLP1-RA
See link to this scientific article in first comment Kevin Pho, M.D.Kevin Pho, M.D
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From the earliest animal-derived exenatide to the human-derived GLP-1RA liraglutide, GLP-1RA has undergone short-acting, long-acting, weekly preparations and oral preparations, similar to the development of insulin analogs
The hallmark of NAFLD is hepatic steatosis, but the disease also encompasses non-alcoholic steatohepatitis (NASH) characterized by hepatic inflammation, hepatocyte damage, and fibrosis, highlighting the potentially progressive nature of the disease
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