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doi: 10.1111/j.1463-1326.2010.01355.x 58 GilbertMPMarreMHolstJJGarberABaeresFMMThomsenHet al

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However, exposure to high glucose conditions did increase mRNA expression and membrane-bound DPP-4 activity in human glomerular (76) and dermal (77) microvascular endothelial cells in vitro , although, interestingly, not in macrovascular (human aortic) endothelial cells (77)

Additionally, oxidative stress plays a key role in bone deterioration, causing inflammation, angiogenesis and synovial proliferation [16]

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