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Involvement of small RNAs in phosphorus and sulfur sensing, signaling and stress: current update

Cold Spring Harb Perspect Med 2(7):a006247a006247

But when Tylenol doses are high, or when glutathione reserves are depleted (from alcohol, poor diet, pregnancy, or chronic illness), the livers defense system collapses

This release of secondary messenger molecules such as IP3 might potentially stimulate the discharge of calcium ions (Ca2+) from the cell's internal stores, while DAG might activate protein kinase C (PKC)