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Systematic reviews and meta-analyses in the endocrinology literature indicate that visceral fat reduction decreases peripheral aromatisation of testosterone to oestrogen, which can improve the hormonal profile

Source: Chang et al., 2020 Antioxidant and Anti-Inflammatory Action Alcohol generates massive oxidative stress

While it has not been conclusively established whether this dysfunction is a cause or consequence of the pathological processes, growing evidence suggests that reduced proteasomal activity may contribute to the accumulation of toxic protein aggregates and the progression of neurodegeneration

TB-500 upregulates vascular endothelial growth factor (VEGF) and related pro-angiogenic factors, promoting new blood vessel formation crucial to tissue repair