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It is bound to a family of six high-affinity IGF binding proteins, IGFBP-1 through IGFBP-6, which sequester it, buffer its free concentration, and in some contexts present it to the receptor and in others withhold it
People with type 1 diabetes also need to keep taking their insulin to avoid diabetic ketoacidosis (DKA), when insulin levels are too low
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It is used to address carnitine deficiency, a condition where the body lacks sufficient levels of this essential nutrient
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