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While very high oral doses (1,000 to 2,000 mcg) can achieve some passive absorption without intrinsic factor roughly 1% of the dose is absorbed passively many clinicians prefer the reliability and rapid correction offered by injections in this population

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We retrospectively analyzed the patients with lipid storage myopathy at the neuropathology laboratory in Gothenburg from 2015 to 2023 and found that only a few had a genetic diagnosis in spite of a MADD-like blood acylcarnitine profile