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Conclusion We have found that insulin and GLP-1 secretions share striking commonalities in signaling, yet each exhibits different unique properties that may have developed evolutionarily and purposefully
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Patients with hypothyroidism who are prescribed semaglutide should be monitored closely, especially during the initial stages of treatment
Some clinicians prefer to reduce the dose stepwise (for example, moving from a higher to lower maintenance dose before stopping completely) to allow for metabolic adjustment and medication changes
Moriarty, N
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