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Quick Answer: GLP-1 medications cause headaches primarily through dehydration from gastrointestinal side effects, blood glucose fluctuations, and metabolic changes during treatment
The 56-week trial involved patients without type 2 diabetes and a BMI of at least 30 (or a BMI of at least 27 if they had treated or untreated dyslipidemia or hypertension)
Analytically, a valid COA should show HPLC purity above 98% and a mass spec confirming the correct molecular weight
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