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Circulation 2018;138:288494.ArticlePubMed 17
"Maternal plasma folate and vitamin B 12 are independent risk factors for neural tube defects"
Patients are encouraged to report any suspected side effects to the MHRA through the Yellow Card Scheme (yellowcard.mhra.gov.uk), which helps monitor the safety of medicines
IDH1 mutations cause significant changes in enzymatic reactions, catalyzing the large-scale conversion of -ketoglutarate (2-KG) to 2-hydroxyglutarate (2-HG), and cause significant changes in the cells metabolic system
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