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However, Rybelsus is not recommended for individuals with a personal or family history of medullary thyroid carcinoma (MTC) or patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) due to the increased risk of thyroid C-cell tumors
However, individual variation exists, and certain populations including older adults, those with baseline sarcopenia, or patients with inadequate protein intake may be at higher risk for clinically significant muscle loss requiring intervention
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