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B-12 occurs naturally and commonly in many foods which you probably already include in your diet

Li et al used tetrahedral framework nucleic acid (tFNA) to synthesize tFNA-Cur, a nanoparticle that can deliver the natural compound curcumin to the bone marrow, thereby enhancing the bioavailability and stability of curcumin

It occurs naturally in human plasma, saliva, and urine, with circulating levels declining from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60 [1]

If you want to explore the broader science behind this approach, start with Why Liposomal Glutathione Is Essential for Daily Wellness

Ozbey, H., Temiz, A