Early data from the TRIUMPH trials is undeniably compelling, showing unprecedented weight loss of up to 28.7% at 68 weeks significantly outpacing tirzepatide in early comparisons (see our Retatrutide vs Tirzepatide comparison guide)
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When to Discard and Provider Factors That May Influence Your Protocol Discard compounded semaglutide immediately if it has been unrefrigerated for more than 2 hours, shows visible particles or discoloration, has exceeded your pharmacy's documented expiration date, or if cold chain integrity is unknown