moa tirzepatide Mechanism of action of tirzepatide GIP = glucose-dependent insulinotropic polypeptide; GLP-1 = glucagon-like peptide 1; LDL = low-density lipoprotein; HR = heart rate FDA Approves Tirzepatide, A Potential

A) all generic cos were very low on their GLP1 forecast before the launch - a few 10s of crores at best in the 1st year eg A top co in India had a 10cr first yr sales forecast and is set to do a multiplier of that On top of that fewer than expected cos have launched B) online sales which is the biggest area of growth on GLP1s (pharmacies / Telehealth) doesnt get captured and so is direct sales

Comparison table What about MariTide and others

Material sold as retatrutide outside clinical trials is supplied for research use only and is not lawful for human or animal administration

A: Participants in clinical trials often have extensive support for concerns like side effect management and dont face real-world barriers such as cost and changing insurance coverage

Now, clearly it takes longer to regain weight, but the same is going to be true for these weight-loss drugs. Yeo also cautioned that the study had a number of limitations and said more research is needed