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Commonly reported side effects include: Nausea, vomiting, or stomach cramps Diarrhoea or loose stools A distinctive 'fishy' body odour, caused by the production of trimethylamine a metabolic by-product of carnitine breakdown in the gut These gastrointestinal effects are more likely at higher doses, particularly above 3,000 mg per day, and are consistent with adverse effects described in the levocarnitine SmPC
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It previously had a twice-daily pill that was also scrapped after similar liver concerns in 2023
In March 2024, Novo Nordisk A/S stated that ozempic (semaglutide) 1.0 mg shows a 24% lower risk of kidney disease events in type 2 diabetes and chronic kidney disease in the FLOW trial
A career FDA official told STAT that staff raised conflict-of-interest concerns and were overruled
