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More people on its highest dose stopped treatment due to nausea, vomiting, and dysesthesia, a tingling or altered skin sensation seen in around 1 in 8 patients, a side effect uncommon with semaglutide or tirzepatide
This aligns with a 2018 clinical trial in Appetite where a preload of gelatin-based dessert reduced ad libitum calorie intake by 20% versus a liquid preload with identical calories
Abstract Background Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has demonstrated cardiometabolic benefits in randomized controlled trials (RCTs)
