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Nat Rev Drug Discov 24 , 631650 (2025)

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Available forms Oral capsules or tablets the most common format for wellness protocols Topical cream or gel may offer transdermal delivery Powder form for compounding allows flexible dosing by qualified pharmacies Subcutaneous injection used in some clinical settings under physician supervision General dosage reference (investigational) Due to Dihexas extraordinary potency and the theoretical concern that excessive HGF/c-Met activation could promote unwanted cellular growth in susceptible individuals conservative dosing and careful medical supervision are strongly emphasized by experienced practitioners

GLP-1 medications are FDA-approved for the treatment of type 2 diabetes and, at higher doses, for chronic weight management in people with obesity