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BPC-157 itself is a gastric pentadecapeptide (GEPPPGKPADDAGLV, 1419.53 g/mol, CAS 137525-51-0), a fragment of the natural protective protein of the gastric mucosa
Thermo Fisher Scientific, Waltham, MA, USA) and -MEM (Thermo Fisher Scientific), respectively, supplemented with 10% fetal bovine serum (FBS) and 1% penicillin-streptomycin (P/S) at 37 C and 5% CO
In addition, some proteins can stimulate tumor cells to switch from oxidative phosphorylation (OXPHOS) to glycolysis, in turn leading to lower levels of GSH, which suppress the activity of GPX4 and boost the accumulation of lipids, thus resulting in ferroptosis [21,22,23,24]
It also raises blood pressure, increasing the risk of stroke
The variability is the practical issue
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