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Genetic Predispositions and Individual Tolerability Individual variations in GLP-1 receptor (GLP1R) and GIP receptor (GIPR) sensitivity are influenced by genetic variants

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Gastric emptying delay Slows digestion, prolonging satiety

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How does the combined use of GLP1-RAs and SGLT2is compare to their separate use in terms of metabolic control, weight change, major cardiovascular events, hospitalizations for heart failure, major renal events, and adverse effects

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5 Glucocorticoid-Induced fat metabolism disorder 5.1 Pathogenesis Obesity is a key feature of GC-induced metabolic syndrome [90] and also is a common feature of Cushings syndrome in patients receiving long-term GCs therapy [91, 92]

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