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Availability of data and materials The data used to support the findings of this study are available from the corresponding author upon request

Phase 2 trial data (NCT04881760) reported diarrhoea in approximately 2030% of participants at higher doses, with symptoms most pronounced during dose-escalation phases

The majority of the reported events occurred in patients who experienced gastrointestinal reactions leading to dehydration such as nausea, vomiting or diarrhea

L-carnitine transports long-chain fatty acids across the mitochondrial membrane to be metabolized

GLP-1 release depends on communication between your gut and brain