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COP1 was first identified in Arabidopsis and characterized as a negative regulator of light-mediated development 14

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Within the lysosome transcobalamin II is degraded and the free cobalamin is released so that it can be used as an enzyme co-factor within the cell

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High throughput testing of drug library substances and monoclonal antibodies for capacity to reduce formation of cystatin C dimers to identify candidates for treatment of hereditary cystatin C amyloid angiopathy

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