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| Michigan Medicine
This difference is due to tirzepatides dual GLP-1 and GIP receptor agonism, which produces stronger effects on gut motility and fluid secretion
In the FIGHT trial on patients hospitalized for HFrEF, Liraglutide did not show benefit on time to death, time to rehospitalization for heart failure, and time-averaged proportional change in N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels from baseline to 180 days [51]
When retatrutide is eventually approved, it may become one of the options we use in medically supervised retatrutide weight loss care, always inside a structured, science-based program and never as a standalone shortcut
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