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Taken together, these pharmacokinetic findings indicate that the centrally mediated effects of GLP-1RAs are likely due to limited brain penetration or action at sites adjacent to the BBB, rather than widespread distribution throughout the central nervous system

October 23, 2009

Instead, Vida said in a statement that its providers adhere to clinical eligibility criteria and plan sponsors' coverage policies when prescribing medication: "At Vida Health, our top priority is delivering personalized, clinically appropriate care for every patient." In an emailed statement, Blue Cross and Blue Shield of Texas, which handles Davis' insurance, said it "is committed to providing its members access to safe, appropriate, and effective health care within the benefits provided by their own health plan." It wouldn't comment on Davis' situation but said it was reaching out to him

Last but not least, due to the lack of sex-stratified data in this study, whether the association of genetically predicted vitamin B12 concentrations with NAFLD risk differs between men and women needs further studies