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[9] Schuster, J., Cycelskij, I., Lopresti, A., & Hahn, A

doi: 10.1002/adma.202207593 56 LiuJHeSLuoY

In cell and animal models, amino acid metabolism not only provides substrates for energy production and biosynthesis, but also regulates the differentiation of macrophages toward M1 or M2 phenotypes by modulating signaling pathways such as STAT1, mechanistic target of rapamycin (mTOR), and NF-B, as well as by affecting epigenetic regulation (59)

The IGF-1/p53-mediated cellular senescence (see above) might also be induced by the STAT3/SOCS pathway

For Some food sources of the vitamin include: However, a person with B12 deficiency may not be able to absorb enough of the vitamin from their diet