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3) Regeneration and Remodeling IGF-1 coordinates immune-matrix interactions during repair, activating satellite cells and shaping matrix turnover mechanisms necessary for efficient regeneration after intense training or deconditioning

In this case, it raises an important point that although these two NTG models both lack glutamate transporters, their cell-type specificity makes the major contributing factor for RGC death in these two models different, highlighting independent values of these two models

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