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In addition, some polyphenols can enhance the anti-tumour effect while antagonizing ototoxicity.Although polyphenols show good application prospects in the prevention and treatment of cisplatin ototoxicity, there are still some problems that need to be solved, such as the low bioavailability of polyphenols, the mechanism of action has not yet been fully elucidated, the optimal dosing regimen has not yet been determined, whether there is any superimposed effect of combining the various types of polyphenols, and whether the oral polyphenols can exert an otoprotective effect through the regulation of the intestinal flora through the intestinal-auricular axis.This study provides new insights into polyphenols as potential drug candidates for CIO by summarising the cytotoxic mechanisms of cisplatin and the mechanism of action of polyphenols targeting these mechanisms in order to retard the progression of CIO
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Description DSIP 5mg Research Peptide Delta Sleep-Inducing Peptide (DSIP) is supplied as a lyophilized research peptide intended for laboratory investigation and analytical applications
If you want a deeper look at the vitamin C side of the routine, our guide on How to Take Vitamin C Correctly for Maximum Absorption is a helpful next read
In 2007, the FDA reported its intent toward banning the use of hydroquinone in non-prescription products due to safety issues but has not implemented any new regulations
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