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described a slight predominance of cases in women (male: female ratio 0.80).15 According to information from the RegiSCAR16 study group, in 2011, there was a higher frequency of a previous history of rheumatological disease or vascular connective tissue disease in 8.5% of patients with DRESS

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Lets look at each of these in more detail: Anxiety disorders, PTSD: As an inhibitory neurotransmitter, GABA puts the brakes on the release of neuropeptides in the brain that activate the hypothalamic-pituitary-adrenal (HPA) axis