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Chronic acid exposure produces cellular injury, inflammation, and structural changes that persist even when reflux is controlled

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69,70,71,72 In synergy with TNF-, IL-4 enhances the expression of vascular cell adhesion molecule-1 and P selectin on vascular endothelial cells, facilitating the trans-endothelial passage of eosinophils from the blood into the respiratory system

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Harmful bacteria and other microorganisms cannot be seen with the naked eye, yet t