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Stacking them could amplify GH and IGF-1 elevation beyond intended levels, increasing the risk of side effects including fluid retention and potential IGF-1-driven proliferative effects
V.GrangeL.SoldiniA.et al (2015)
PMID: 21 CarCRouaultCLe RoyTPoitouCAron-WisnewskyJTorciviaAet al
Efinopegdutide (NNC0194-0499) activates GLP-1R and GCGR but lacks meaningful GIPR activity and sits closer to a dual GLP-1/glucagon class
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