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they reclaim energy, improve metabolic markers, and keep the weight off

After 2 weeks of treatment, mice treated with GLP-1MK-801, as well as those subjected to calorie restriction or GLP-1 monotherapy, demonstrated enhanced glucose tolerance compared with mice that were treated with the vehicle or MK-801 monotherapy (Extended Data Fig

This can lead to further health complications like bone loss or anemia

This happens through several different mechanisms, some of which are not fully understood

Additional health benefits include reduced blood pressure, a lower risk of stroke, cancer, non-alcoholic fatty liver disease (NAFLD), and cardiovascular disease