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People with chronic inflammation, autoimmune diseases, or pain syndromes often report significant improvements without harsh medication

Feb 2020;5(1):132-136

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Contraindications and precautions Consider avoiding DSIP or consulting a physician if: Pregnant or breastfeeding (insufficient safety data) Taking naloxone or other opioid antagonists (may block effects) Using medications metabolized by peptidases (potential interactions) History of immune disorders (theoretical immunogenicity concern) Already using multiple sleep medications Drug interactions Because DSIP degrades via amino-peptidases in blood, medications affecting these enzymes (like the ACE inhibitor captopril) could theoretically alter DSIP metabolism

B12 injections are most clearly indicated for people who cannot absorb B12 adequately through their gut