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Ferroptosis is closely related to cancer treatment, neurodegenerative diseases, ischemiareperfusion of organ, neurotoxicity, and others, in particular, in the field of neurodegenerative diseases treatment has aroused peoples interest
IP3 might then prompt the release of calcium ions (Ca2+) from intracellular reserves, whereas DAG potentially activates protein kinase C (PKC)
The transfection assay clearly demonstrated a decrease in glutamine consumption due to reduced GLS1 levels, whereas this was not as apparent in the dendriplex PURE G4 -LA 12 -anti- GLS1 -siRNA assay
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