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Each component has distinct pharmacokinetic properties, with phentermine having a 20-hour half-life and topiramate extending to 21 hours, supporting twice-daily dosing regimens (Hendricks et al., Obesity, 2014)

A study published in January 2022 linked Research published in December 2022 also reported the use of GLP-1 receptors was Glucagon-like peptide-1 receptor agonists (GLP-1 agonists) are a type of medication used to help manage type 2 diabetes

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Incidentally, this group also lost the most weight, 16.88kg, compared to the 11.19kg lost by the exercise group and the 13.74kg by the liraglutide group