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For instance, cocaine upregulates miR-212/132 in the striatum, which feeds back via CREB, MeCP2 and BDNF to limit cocaine reinforcement 180
Jang H, Hong K, Choi Y
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Here, it tweaks the balance of neural signals, releases satiety signals, suppresses hunger, cuts down on the desire to eat, controls calorie intake from the source, and helps stabilize blood glucose in a reasonable range
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