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In renal tubular epithelial cells treated with calcium oxalate (CaOx) to induce kidney stone formation, CHAC1 expression increases alongside a decreased GSH level, reduced GPX4 activity, increased iron and MDA content and elevated ROS and lipid peroxidation
Keeping a good level of selenium might be harder than it looks
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Seiwerth S, Sikiric P, et al
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