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These structural proteins provide skin elasticity and firmness, and their depletion during quick weight loss leads to sagging skin, wrinkles, and volume loss in both facial and body areas
GLP-1 receptor agonists are now widely used, both in lower doses for treatment of type 2 diabetes and in higher doses to treat obesity
See what a recent study showed in our article about supplements and GLP-1 meds
Berthet et al., 2013
I will say that as of March 2023, I am surprised to find that most availability has seemingly done a 180 from where it was for most of last year. The bottom line From the FDA perspective, with few exceptions, health care professionals generally may choose to prescribe or use a legally marketed human drug or medical device for an unapproved or uncleared use when they judge that the unapproved use is medically appropriate for an individual patient, says Tantibanchachai
