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The peptide activates the FAK-paxillin pathway essential for cell migration, while influencing EGR-1 and growth hormone receptor expression

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On the other hand, Th17 cells and IL-17 present in the skin activate a nearby inflammatory response mediated by neutrophils, which ultimately results in damage to the tissue (122, 123)

At the population level, the overall trajectory was one of disease progression rather than improvement: the mean MELD-3 score increased by 2.69 points from baseline to follow-up along with statistically significant changes indicating hepatic decompensation